A cafeína reduz a atividade dos músculos que levam o óvulo desde os ovários até o útero, o que diminui a chance de a mulher engravidar. Essa é a conclusão de um estudo realizado pela Universidade de Nevada, nos Estados Unidos, e publicado na revista científica British Journal of Pharmacology.
Sean Ward, professor de Fisiologia e Biologia Celular da Faculdade de Medicina da Universidade de Nevada e coordenador do estudo, explica que os óvulos humanos são muito pequenos, mas precisam atingir o útero para que a mulher fique grávida. Embora esse processo seja muito importante, existem poucas informações a respeito de seu mecanismo. O que os cientistas sabem é que as tubas uterinas possuem células com cílios que, por meio de contrações, movimentam o óvulo até o útero.
Ao estudar o útero de camundongos, os pesquisadores descobriram que a cafeína interrompe a ação das células presentes na parede das tubas uterinas. Como são essas células que coordenam as contrações, os óvulos não conseguem mais se mover quando elas são inibidas. De acordo com Ward, essas células são mais importantes do que os cílios para realizar a movimentação.
- Isso dá uma explicação sobre por que as mulheres que consomem bastante cafeína geralmente demoram mais para engravidar do que as que não tomam a substância.
- Além de ajudar mulheres que estão com dificuldade para engravidar, uma melhor compreensão de como funcionam as tubas uterinas vai ajudar os médicos a tratar inflamações na região pélvica e doenças sexualmente transmissíveis.
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Mostrando postagens com marcador INFERTILIDADE FEMININA. Mostrar todas as postagens
Mostrando postagens com marcador INFERTILIDADE FEMININA. Mostrar todas as postagens
quinta-feira, 21 de julho de 2011
segunda-feira, 30 de maio de 2011
Caffeine May Interfere With Fertility in Women
Caffeine, a known stimulant, has been shown to cause rapid heart rate, nausea, anxiety and depression. Now, new research reveals that caffeine consumption may make it harder for a woman to get pregnant.
By analyzing fallopian tubes in mice, researchers found that caffeine interferes with muscle contractions that help eggs travel from the ovaries through the fallopian tubes and into the womb -- a process critical for a successful pregnancy.
"Our experiments were conducted in mice, but this finding goes a long way towards explaining why drinking caffeinated drinks can reduce a woman's chance of becoming pregnant," Sean Ward, professor at the University of Nevada School of Medicine, said in a journal news release.
"This provides an intriguing explanation as to why women with high caffeine consumption often take longer to conceive than women who do not consume caffeine," Ward added.
Caffeine is found in coffee, tea, colas, chocolate and certain medications.
Researchers noted that the study's findings, published May 26 in the British Journal of Pharmacology, could further the understanding and treatment of infertility as well as some complications of pregnancy.
Previously, it was thought that eggs moved through the fallopian tubes assisted by hair-like projections called cilia, but this study suggests that specialized pacemaker cells coordinate the contractions that push the eggs along.
"As well as potentially helping women who are finding it difficult to get pregnant, a better understanding of the way fallopian tubes work will help doctors treat pelvic inflammation and sexually transmitted disease more successfully," said Ward. "It could also increase our understanding of what causes ectopic pregnancy, an extremely painful and potentially life-threatening situation in which embryos get stuck and start developing inside a woman's fallopian tube."
SOURCE: British Journal of Pharmacology, news release, May 26, 2011
nlm
By analyzing fallopian tubes in mice, researchers found that caffeine interferes with muscle contractions that help eggs travel from the ovaries through the fallopian tubes and into the womb -- a process critical for a successful pregnancy.
"Our experiments were conducted in mice, but this finding goes a long way towards explaining why drinking caffeinated drinks can reduce a woman's chance of becoming pregnant," Sean Ward, professor at the University of Nevada School of Medicine, said in a journal news release.
"This provides an intriguing explanation as to why women with high caffeine consumption often take longer to conceive than women who do not consume caffeine," Ward added.
Caffeine is found in coffee, tea, colas, chocolate and certain medications.
Researchers noted that the study's findings, published May 26 in the British Journal of Pharmacology, could further the understanding and treatment of infertility as well as some complications of pregnancy.
Previously, it was thought that eggs moved through the fallopian tubes assisted by hair-like projections called cilia, but this study suggests that specialized pacemaker cells coordinate the contractions that push the eggs along.
"As well as potentially helping women who are finding it difficult to get pregnant, a better understanding of the way fallopian tubes work will help doctors treat pelvic inflammation and sexually transmitted disease more successfully," said Ward. "It could also increase our understanding of what causes ectopic pregnancy, an extremely painful and potentially life-threatening situation in which embryos get stuck and start developing inside a woman's fallopian tube."
SOURCE: British Journal of Pharmacology, news release, May 26, 2011
nlm
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